Formulation Designing of Ungual Drug Delivery System of Fluconazole Nail Lacquer and Characterization
The topical route of administration is more effective route as compared to the oral route in the treatment of fungal infections of nail. The formulation objective was to provide a sustained release of antifungal drug over extended period of time, so as to reduce frequency of administration, improve clinical efficacy and improve patient compliance. The purpose of the present study was to formulate Fluconazole nail lacquer containing two different penetration enhancers, for the treatment of onychomycosis and to find out which concentration of penetration enhancers gave better release of the drug. The formulation showed good non-volatile content, gloss, smoothness of flow, drug release, drug content estimation and antifungal activity. The in-vitro studies were carried out in Franz diffusion cell using phosphate buffer(pH 7.4) as medium. Whereas the permeation studies were carried out using hooves membrane. The percentage cumulative drug released was determined by UV spectrophotometer. The formulation containing ethyl cellulose (10%w/v) and Thioglycolic acid(3%v/v) and Dimethyl sulfoxide(3%v/v)showed highest release of drug. FTIR studies revealed that drug and excipients are compatible. Stability studies was done as per ICH guidelines for 1 month, which revealed no significant change with respect to the evaluations conducted before stability charging. The sensitivity of Fluconazole against Candida albicans was determined by measuring zone of inhibition by comparing with the standard drug for onychomycosis treatment.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
The Smart Food Choice: A Study on the influence of Front of Package Nutritional label on the perceptions and buying behavior of Consumers
India is the world’s second largest producer of food next to China and has potential of being the biggest with food and agriculture sector. The Food Processing industry is the 5th largest industry in India in terms of production, consumption, export and expected growth. Among the various sectors of Food Processing industry, ready to eat food product industry is growing at the fastest pace of 30 % p.a. There are nearly 100 international, national and local players already operating in industry and equal numbers of players are likely to enter in the market in coming years due to its huge growth potential. Ready to eat food products being product of low involvement category, a little differentiation exists among the product sproduced by various players of the industry so to differentiate their products companies make use of various marketing tools. One of the most prominent tools used in the industry is packaging. The companies make use of various packaging elements to differentiate their products. This study is undertaken to analyze the influence of Nutritional labels like free from trans fat and cholesterol provided on the packages of Namkeens on the perceptions and buying behavior of consumers of Rajkot. To attain the aim of study, a sample of 200 respondents was taken. The research paper is structured into five sections. The first section focuses on the introductory part of the paper. It highlights the international, national and local scenario of Food processing industry. The second section focuses on the aspects like definition of Packaged food, importance and role of packaging in the category and main objectives of the study. The third section discusses the previous studies parallel to the current study. It also highlights how the current study is different from the previous studies. The fourth section reveals how the research has been undertaken. The last section i.e. fifth section narrates the findings of the paper, limitations of the study, policy recommendations and concluding remarks.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
The Relationship between Test Anxiety and Learners' Overall Achievement in the English Course
Among all researches in the field of learners’ overall achievement, the effect of test anxiety of test takers’ has rarely been explored. And also, this present study is an effort to examine the anxiety of pupils in relation with overall achievement in the English course and the effect of their behavior on their performance on overall achievement test in the English course at the end of term. Data was collected by using the anxiety questionnaire developed by Richard Driscoll. A total of 200 participants were selected for this study. Accordingly, a standardized anxiety questionnaire was administered to 100 female and 100 male pupils in order to discover whether there is a relationship between test anxiety and learners’ overall achievement in the English course in the middle school in different genders. The findings have implications for testing, teaching, and syllabus design.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Relationship between Intercultural Competence and Reading Skills among EAP Students
This article reports a study investigating the existence of any statistically significant correlation between intercultural competence and reading comprehension ability among EAP university students. The participants of the study were about 120 participants (male = 50, female =70, mean age = 26.85). In so doing, first of all, the Persian translation of intercultural sensitivity questionnaire was used. Moreover, to provide evidence for the dependent variable of this study, that is, reading comprehension, specialized readings (Academic Medical standardized readings) which were related to the aspects of medical texts were given to the students. Based on Pearson product moment correlation, it was found that there was a strong positive correlation between Intercultural competence and reading comprehension ability, indicating that individual‘s performance on Academic readings comprehension got better with respect to higher Intercultural competence. It was also found that there was a significant positive correlation between variable-specific IC and performance on Academic reading comprehension.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Checking the effect of organizational justice on the social capital of employees on service financial institutes (Case study of TEJARAT bank in ZANJAN)
In recent years according to the increase of the organizational justice and the effects of the that in results of the organizational systems in case of the reaching the goals and keeping the systems, it took different models and patterns and created new challenging system in order to prevent failing and collapsing and keep system away from dangers which are caused by fast environmental alters, though recent experiments are about checking the effect of the understandings from the organized justice based on the publican fund of the Tejarat Bank’s employees . for this experiment about 4 theories are designed which are in case of the gathering information and ideas from Fernandez questionnaire 2006 and Publican fund questionnaire 1390 which in the end a 46 questions in form of a questionnaire has been formed and given among the Tejarat Bank employees which according to the normal grade of the alters and independency of mistakes and fouls from regression for experiments of theories and from analyzing experiment and toki in grading of organized justice alters in SPSS19 software as results showed up that organized justice and it’s alters which conclude distributive justice , has positive and useful effects on the publican fund of the employees and also grading the organized justice alters showed up that distributive justice comes in the first place and procedural justice comes after it means the second place and in the end interactional justice took the third place of our grading system .
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
The Concept of Sustainable Development towards Multifunctional Products
This paper will explain more detail about the way to produce product which is designing and develop by concern the criteria of sustainable. Multipurpose Iron Board is one of the product with applied the concept of sustainability. Multipurpose Iron Board can perform a variety of uses other than iron board itself. In sustainable design, it’s able to function as a ladder and chair too. This product is easy to store, easy to carry, lightweight and durable. In addition, the design of which was developed also emphasized aesthetic values. Ergonomic factors are also taken into account so that the user can use the product properly and safely. Anthropometric data is referenced to ensure product will be produce by full fill the ergonomic factors. This product is designed by considered consumer demand through market survey. The current issue such as limited space and less storage will be overcome through the use of this product.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
The Investigation of the Impact of Intellectual Capital on Codification of Knowledge Strategy in Oil Industry
The present study intends to review the previous researches carried out on the field of knowledge strategy codification and investigate the influence of intellectual capital on the knowledge strategy codification in Islamic Republic of Iran’s oil industry. The primary objective of this study is to analysis the impact of intellectual capital on codifying knowledge strategy in oil industry. This study is categorized as an applied one and has been carried out through the descriptive method of research, and the method used for employing variables is a combination of quantitative (descriptive – survey) and qualitative (content analysis) methods of research. Moreover, for the exploratory factor analysis of the intellectual capital indicators and knowledge strategy and to assess the validity of the questionnaire, the exploratory and confirmatory factor analysis techniques and KMO indices have been used, to determine the reliability of the questionnaire, the technique of Cranach’s alpha has been applied, and to discover whether the hypotheses are void or confirmed, inferential statistics been employed. To examine the hypotheses, correlation coefficients have been used, and to assign rank orders to variables, Friedman test has been applied.The result of the study reveals that there is a positive and meaningful relationship between intellectual capital and knowledge strategy. Another finding of the study is that human is the significant factor in intellectual capital, and knowledge development plays the most crucial role in knowledge strategy.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
The effect of pre drying, slices dimensions and Psyllium seed hydrocolloid-coating on oil uptake in potato slices during deep fat frying
Nowadays, consumption of fried potatoes is highly growing and due to its high oil uptake during the process, it makes a lot of calories which are harmful to human Health; so, attempts to reduce the amount of absorbed oil will improve the health of society. In this research the effect of Psyllium seed hydrocolloid as coating material (0.5, 1%), changes in slices dimensions (6×1.25×1.25, 6×1.5×1.5) and predrying (reducing moisture to 60%) are assessed on the oil uptake by potatoes in the deep fat frying process individually and together. Results show that coating by Psyllium seed hydrocolloid due to its blocking nature causes decreasing the loss of moisture during the frying while water can control the amount of absorbed oil. Increasing in the concentration of hydrocolloid solution decreased the efficiency of frying, moisture (resulted from coating) and the tissue smoothness. Taste and color improved by predrying. The loss of moisture, the amount of coating and reduction in absorbed oil, also increased. Reducing in slices dimensions increased the efficiency of frying, coating percent and the tissue smoothness.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Evaluation of Physicochemical Properties of Fermi macaroni after Adding Spray Dried Lactic Acid Sourdough
Sourdough fermentation is one of the oldest biotechnological methods of food preparation. Macaroni, as one of the world's most widely consumed cereal products, used in large quantities, because of its nutritional value, significant amounts of complex carbohydrates, protein, vitamin B & iron. In this study, We evaluated physicochemical properties of fermi macaroni after adding spray dried lactic acid sourdough (12, 8, 5% w/w) of three species of Lactobacillus acidophilus, Lactobacillus cazei & Lactobacillus plantarum in 10 treatments of semolina with 88, 92, 95 & 100 grams. As a result, according to the obtained data, the sample containing 8% Lactobacillus acidophilus was chosen as the sample with superior physicochemical properties.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Sensitivity comparison of the sugarcane mill delay in Iran. Green sugar cane is more sensitive or burned?
Sugarcane is one of the industrial crops used as raw material for several major and minor industries. In Khuzestan, which contains most of the sugarcane farms of Iran, sugarcane is harvested either in green or burnt method. Mechanized harvesting has been replaced by manual harvesting during recent years. Delay in milling of the harvested sugarcane is caused by different reasons in agro-industry units, in addition, methods of harvesting including green and burnt harvesting can cause qualitative and quantitative losses of canes. Thus, a split-plot in time design was executed, with the randomized complete block basic design in 5 replications, in Hakim Farabi agro-industry in 2015. The results showed that the interaction between time delay and harvesting method was significant in 5% level of probability in the main traits of sugarcane i.e. the amount of yellow and white sugar which is affected by other qualitative and quantitative factors. In such a way that the amount of yellow and white sugar during 5 days delay in burnt sugarcane was respectively 1.96 and 1.63 tons per each 100 tons, whereas the amount was 1.3 and 1.08 tons in green harvesting of sugarcane. Thus, compared to burnt sugarcane, green harvesting is less sensitive toward time delay. The invert, which represents loss of sugarcane quality, was separately significant in harvest and time treatments respectively in 1% and 5% levels of probability; in such a way that was 1.7 times higher in burnt sugarcane compared to green one day. The amount of invert in 5th day was 1.35 higher than 4th day.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]