Archives-J 

The article focuses on the problem of foreign language training of future specialists as an integral part of the professional training of students of different specialties. The authors analyze the modern features of a foreign language training at the present stage of the society development. The article considers the potential of professional-oriented language for training future specialists that will enable the 21st century professionals to fulfill their professional responsibilities, to be more adaptable and flexible to the challenges of rapid development of society and technology.

The aim of the present study was to improve the solubility and bioavailability of a poorly water-soluble drug in human body, using a solid dispersion technique. Solubility and dissolution rate is an important physicochemical factor affecting absorption of drug and its therapeutic effectiveness. Consequences of poor aqueous solubility would lead to failure in formulation development. The poor solubility of drug substances in water and their low dissolution rate in aqueous G.I.T fluid often leads to insufficient bioavailability. In the present investigation, an attempt was made to improve the solubility and dissolution rate of a poorly soluble drug, Eprosartan by solid dispersion method using skimmed milk powder as carrier. Four different formulations were prepared with varying drug:carrier ratios viz.1:1, 1:3, 1:5 and 1:9 and the corresponding physical mixtures were also prepared. The formulations were characterized for solubility parameters, drug release studies and drug-polymer interactions by using phase solubility studies, dissolution studies; XRD analysis, FTIR spectrum, TLC analysis and UV overlay spectra. All the formulations showed marked improvement in the solubility behaviour and improved drug release. Formulation containing drug: polymer ratio of 1:9 showed the best release with a cumulative release of 82.67 % as compared to 6.919 % for the pure drug. The interaction studies showed no interaction between the drug and the carrier. It was concluded that skimmed milk powder as a carrier can be very well utilized to improve the solubility of poorly soluble drugs.

The study aims to investigate projects submitted by graduating students to the College of Engineering of Afe Babalola University, Ado-Ekiti, Nigeria using citation analysis. A descriptive survey design was used for the study. A total of 406 copies of undergraduate projects submitted between 2015 –2017 to the College of Engineering of the institution were retrieved. Data were extracted manually from the title pages and reference lists of each of the project examined and analyzed. The findings show that from 12,741 citations made in all the projects submitted for the 7 programmes run in the College of Engineering, information materials mostly cited by students is journals followed by books and seminar/conference proceeding. The average number of citation per project is 31.38. The students cited more of recent materials, and more of foreign authors compared to that of Nigerians authors. The research provides an opportunity for the library in building their collection towards the area that will meet the needs of engineering students since the analysis shows the preferred formats of resources accessed by the students in their discipline. It was recommended that the supervisor should put more efforts in guiding the students attached to them on how to reference and carry out proper citations of materials consulted.

If a nuclear reactor happened to be prompt critical - even very slightly - the number of neutrons would increase exponentially at a high rate, and very quickly the reactor would become uncontrollable by means of cybernetics. The prompt neutron flux spectrum of the compact core of the Ghana’s miniature neutron source reactor (MNSR) was understudy using the Monte Carlo method. 20484 energy groups combined for all three categories of the energy distribution, thermal, slowing down and fast regions were modeled to create small energy bins. The moderator, the inner irradiation channels, the annulus beryllium reflector and the outer irradiation channels were the region monitored. The prompt thermal neutrons recorded it highest flux in the inner irradiation channel with a peak flux of (1.2091 ± 0.0008) × 1012 n/cm2•s, followed by the outer irradiation channel with a peak flux of (7.9393 0.0056) × 1011 n/cm2•s. The beryllium reflector recorded the lowest flux in the thermal region with a peak flux of (2.3328 0.0004) × 1011 n/cm2•s. The peak values of the thermal energy range occurred in the energy range 1.8939× 10-08 MeV – 3.7880× 10-08 MeV. The inner irradiation channel again recorded the highest flux of (1.8361 0.0301) × 1009 n/cm2•s at the lower energy end of the slowing down region between 8.2491× 10-01 MeV – 8.2680 × 10-01 MeV, but was over taken by the moderator as the neutron energies increase to 2.0465 MeV. The outer irradiation channel recorded the lowest flux in this region. In the fast region, the core, where the moderator is found, the moderator recorded the highest flux as expected at a peak flux of (2.9143 0.0195) × 1008 n/cm2•s at 6.961MeV. The inner irradiation channel recorded the second highest flux while the outer channel and annulus beryllium recorded very low flux in this region. The final k-effective contribution from only prompt neutrons is 0.9956, hence the Ghana MNSR not prompt critical

In this manuscript, we will discuss a definition of Laplace transforms with some of their properties. with common applications. This will be according to some types and ranks of differential equations. We will also show how to find the inverse Laplace transform. We also showed what are differential equations of the third order and how the Laplace transform is applied to them. In addition to (Heterogeneous Linear Equations), which is a type of differential equation. The articles of this manuscript were interspersed with a mention of some types of solutions.

This paper is deliberate the psycho study in earthquake affected area in Nepal. Earthquake is one of the fatal natural disasters we have regularly experienced. Nepal and its adjacent areas are vulnerable to very high magnitude of earthquake. On the basis of investigation it has been found that recent earthquakes had destructed many human lives and their properties in Nepal and north India. The earthquake was considered to be the main cause for avalanches, landslides, slumps, many creaks and fissures in the adjacent area of Nepal. The study endeavors to examine the nature, extent, causes and consequences of the tremor of quakes.

The experimental and theoretical study on the structure and vibrations of 1,2,4-triazine-3,5(2H,4H)-dione have been carried out by ab initio HF and DFT/B3LYP method with 6-311++G(d,p) basis set. The FT-IR and FT-Raman spectra of the title compound have been recorded. The molecular structure, vibrational wavenumbers, infrared intensities and Raman activities were calculated. The force constants obtained from this study have been utilized in the normal coordinate analysis. The temperature dependence of thermodynamic properties has been analyzed. Molecular electrostatic surface potential (MESP), total electron density distribution and frontier molecular orbital’s (FMO) are constructed at B3LYP/6-311++G(d,p) level to understand the electronic properties. The atomic charges, electronic exchange interaction and charge delocalization of the molecule have been performed by natural bond orbital (NBO) analysis.

The Americium-Beryllium neutron irradiation facility at the National Nuclear Research Institute (NNRI), Ghana, was re-designed with a 20 Curie source using MCNP5 to investigate the maximum amount of flux that is produced by the source. The main objective was to enable us harness the maximum amount of flux for optimization of neutron activation analysis. The design was compared with the values recorded in the existing Am-Be source design. The thermal neutron flux ranges from (1.80 ± 0.0008) × 106 n/cm2.s to (2.28 ± 0.0008) × 105 n/cm2.s. The epithermal neutron flux ranges from (8.20 ± 0.0008) × 105 n/cm2.s to (3.73 ± 0.0008) × 104 n/cm2.s and that of the fast neutron flux ranges from (4.20 ± 0.0008) × 105 n/cm2.s to (1.72 ± 0.0008) × 104 n/cm2.s. The keff of the Am-Be source design was obtained as 0.00115 ± 0.0008.

The Retail employees are driven by the same universal motivational theories. Though their life style and the aspirations in economic terms are different in the Indian society, their behaviour towards the motivational stimuli are almost the same as employees of other industry. When we apply Maslow’s need hierarchy and check where the preference of the Retail employees lay. They are concentrated as social and elite needs as the lower physiological and basic needs are taken care of easily given their economic stand in the society. Work is an important event, a fact that is inevitable in the life of an individual whatever form, it is done; it is an activities and source of satisfaction ones needs. Employee try to find satisfaction in what they do and as a result the manager should be able to understand the problems faced by his workers and find a way of satisfying their needs and aspiration The general assumption is that an adequately motivated worker will in turn give in his or her best towards the attainment of a general consensus. The observations of the present study corroborate the fact that, there is a strong positive relationship between employee motivation and His/her productivity. 98% of the employees responded that they will get motivated by their working environment. The kind of monitoring they have from their managers, the compensation what they get from the company is also important motivator to retain them. Over 90% of the employees say that quality of their working environment motivates them to work with enthusiasm, working culture, behaviour and attitude about their work. Based on the above respondents response we can say that there is a relation between employee motivation and his/her productivity.

The aim of the present study was to design and develop a self microemulsion drug delivery system (SMEDD) of Atorvastatin Calcium and evaluate its release kinetics by using mathematical models. Suitable oil, surfactant and cosurfactant were selected based on the solubility, HLB value and biocompatibility. Pseudo-ternary phase diagrams were constructed to identify the microemulsion existing zone and to get a tentative surfactant to cosurfactant ratio. Atorvastatin Calcium loaded SMEDD was developed and characterized for particle size, zeta potential, surface morphology, drug entrapment and comparative in vitro drug release study. Different dissolution models were applied to drug release data in order to evaluate release mechanisms and kinetics and the criterion for selecting the most appropriate model was based on linearity (coefficient of correlation). % Transmittance, Particle size and zeta potential of the formulation containing Labrafac PG as oil, Accenon CC as surfactant and Transcutol P as cosurfactant were found to be 99.87%±1.2, 31.82 nm± 1.15 and -15.8 mV± 1.13 respectively. The drug release data fit well to Koresmayer Peppas equation plot (r2 =0.981) indicating the dissolution rate limited drug release from a SMEDD formulation. Drug release mechanism was found as a Super case-II transport, (i.e., n value-1.229).