Physiology and Anatomy

 Describe the modalities for the management of anaplastic thyroid carcinoma in its sarcomatoid form. Material and method: We report the case of a 45-year-old woman who presented with anaplastic thyroid carcinoma in its sarcomatoid form. Clinical case: This is a 45-year-old patient admitted to the emergency department for the management of inspiratory dyspnea on a large mass in the anterior cervical region that has been developing for more than 3 months. A cervicothoracic CT scan was performed urgently showing an enormous thyroid mass of malignant appearance at the expense of the left thyroid lobe with extension to the other lobe, associated with thrombosis of the internal jugular vein and the superior vena cava, as well as a right pulmonary embolism. A surgical decision for tumor reduction with extemporaneous pathological examination associated with a tracheostomy was taken. The definitive anatomopathological examination revealed after immunohistochemical study anaplastic thyroid carcinoma in its sarcomatoid form Conclusion: The therapeutic approach to anaplastic cancers has changed in a few decades. Surgical treatment of goiters has reduced the incidence of these cancers, access to preoperative cytological diagnosis sometimes allows early management, at the stage of emerging intrathyroidal anaplastic foci in differentiated cancers. Combined treatments give back a place to surgery. 

we report a clinical case of a rare entity, the zenker's diverticulum, discovered in a young man, we present the clinical dilemma and the management challange.

Laryngomalacia is the most common cause of stridor in infants-strider results from upper airway obstruction due to supraglottic tissue collapse. Most causes of laryngomalacia are mild and self solve investigation and intervention required in severe causes. There is a strong association with gastroesophgeal reflux disease in patients with laryngomalacia and thus medical treatment with antireflux medications surgical treatment is preferred, while it indicate supraglottoplasty, severe cases are reserved. Proper identification of those patients when requires medical and surgical invention is key to providing with successful outcomes.

The detection rate of pancreatic cystic lesions has increased since the current use of high resolution imaging. CT-scan, MRI and echo-endoscopy are diagnostic modalities. The pseudocyst is the most common lesion. It is benign and can be managed by endoscopic treatment. Pancreatic cancer accounts for 2% of all tumors, yet it is the fifth leading cause of cancer death. The surgical treatment of these lesions should be discussed within a multidisciplinary team. The interest of this observation lies in the rarity of the published case, both in terms of the location of the tumor and the clinical and radiological presentation leading to a benign tumor of the pancreas which sometimes poses diagnostic difficulties and justifies a discussion multidisciplinary.

Takayasu's disease is an inflammatory arteritis particularly rare in children and is often difficult to diagnose due to the large clinical polymorphism and the absence of specific biological criteria. We report a rare case of takayassu disease revealed by pyoderma gangrenosum in a child. The diagnosis was confirmed by imaging, which showed multifocal arterial damage suggestive of vasculitis. 

Gardner's fibroma is a rare benign soft tissue tumor most commonly occurring between infancy and adolescence. Approximately 70% are associated with familial adenomatous polyposis (FAP) and Gardner’s syndrome which are inherited in an autosomal dominant manner. We report the observation of a young 16-year-old patient who underwent surgical resection of a large right lateral cervical mass, whose anatomopathological analysis of the operative specimen confirmed the diagnosis of Gardner's fibroma. Considering the association between this histological type and the FAP, a family survey and an endoscopic digestive exploration in search of a recto-colic polyposis coming back negative. The diagnosis is an isolated sporadic Gardner's fibroma.

Hepatic artery pseudoaneurysm is a rare complication of traumatism of the bile duct. The objective of this work is to be able to suspect this complication in case of hemobilia or hepatic colic and to make the diagnosis by hepatic Computed tomography angiography. Endovascular treatment is the least invasive method and should be considered urgently.We report a case of a young boy whose diagnosis was established by computed tomographic angiography of the hepatic artery after having presented Quincke’s triad.

The infectious disease pulmonary tuberculosis (PTB) and the non-infectious disease diabetes mellitus (DM) constitutes major health problem in the society. Many research studies acknowledging the negative health impacts of DM on patients with PTB. In this study 500 PTB patients with DM had been subjected to screen for anemia. Hb % had been studied to evaluate their anemic status. The study results had been strongly proving about…% of the PTB patients were found to be affected by anemia. From this study results, it has been concluded that the patients with DM and PTB had been documented with mild to severe type of anemia . These patients require special care to treat anemia which in turn helps in the management of PTB and DM.

Pseudo-Ludwig's phenomenon, a rare clinical entity, is characterized by non-infectious upper airway obstruction resulting from spontaneous hematoma in the sublingual area. We describe a case of pseudo-Ludwig's phenomenon in patient on anticoagulants with deranged coagulation profile.

Sarcomatoid variant of urothelial carcinoma (SVUC) is an uncommon histological variant of urothelial carcinoma. Sarcomatoid carcinomas are aggressive malignancies with poor prognosis, which by definition are biphasic neoplasms with both an epithelial and a mesenchymal component. There is no consensus opinion on the best treatment modalities for this tumor. Herein on are reported 5 cases of SVUC with a brief review of the literature. The data was collected from the medical records in the Department of Urology, at the University Hospital Center of Rabat Morocco during the period from January 2014 to December 2017.